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Centrally circulating α-klotho inversely correlates with human obesity and modulates arcuate cell populations in mice

OBJECTIVE: Our laboratory recently identified the centrally circulating α-klotho protein as a novel hypothalamic regulator of food intake and glucose metabolism in mice. The current study aimed to investigate novel molecular effectors of central α-klotho in the arcuate nucleus of the hypothalamus (A...

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Detalles Bibliográficos
Autores principales: Landry, Taylor, Li, Peixin, Shookster, Daniel, Jiang, Zhiying, Li, Hongli, Laing, Brenton Thomas, Bunner, Wyatt, Langton, Theodore, Tong, Qingchun, Huang, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777546/
https://www.ncbi.nlm.nih.gov/pubmed/33301986
http://dx.doi.org/10.1016/j.molmet.2020.101136