Cargando…
Centrally circulating α-klotho inversely correlates with human obesity and modulates arcuate cell populations in mice
OBJECTIVE: Our laboratory recently identified the centrally circulating α-klotho protein as a novel hypothalamic regulator of food intake and glucose metabolism in mice. The current study aimed to investigate novel molecular effectors of central α-klotho in the arcuate nucleus of the hypothalamus (A...
Autores principales: | Landry, Taylor, Li, Peixin, Shookster, Daniel, Jiang, Zhiying, Li, Hongli, Laing, Brenton Thomas, Bunner, Wyatt, Langton, Theodore, Tong, Qingchun, Huang, Hu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777546/ https://www.ncbi.nlm.nih.gov/pubmed/33301986 http://dx.doi.org/10.1016/j.molmet.2020.101136 |
Ejemplares similares
-
Central α-Klotho Suppresses NPY/AgRP Neuron Activity and Regulates Metabolism in Mice
por: Landry, Taylor, et al.
Publicado: (2020) -
Administration of alpha klotho reduces liver and adipose lipid accumulation in obese mice
por: Rao, Zhijian, et al.
Publicado: (2019) -
ARC(AgRP/NPY) Neuron Activity Is Required for Acute Exercise-Induced Food Intake in Un-Trained Mice
por: Bunner, Wyatt, et al.
Publicado: (2020) -
The effects of exercise on hypothalamic neurodegeneration of Alzheimer’s disease mouse model
por: Do, Khoa, et al.
Publicado: (2018) -
AgRP/NPY Neuron Excitability Is Modulated by Metabotropic Glutamate Receptor 1 During Fasting
por: Laing, Brenton T., et al.
Publicado: (2018)