Cargando…
1190. Dual-Plasmid Technology for Precision Genome Editing in Staphylococcus aureus
BACKGROUND: Genetic manipulation of Staphylococcus aureus (both methicillin sensitive S. aureus, MSSA, and methicillin resistant S. aureus, MRSA) poses a technical challenge due to poor transformation efficiency, limited endogenous DNA repair activity, lineage-specific methylation patterns and intri...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777601/ http://dx.doi.org/10.1093/ofid/ofaa439.1375 |