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1190. Dual-Plasmid Technology for Precision Genome Editing in Staphylococcus aureus
BACKGROUND: Genetic manipulation of Staphylococcus aureus (both methicillin sensitive S. aureus, MSSA, and methicillin resistant S. aureus, MRSA) poses a technical challenge due to poor transformation efficiency, limited endogenous DNA repair activity, lineage-specific methylation patterns and intri...
Autores principales: | Reish, Jennifer, Dey, Somrita, Penewit, Kelsi, Salipante, Stephen J, Berti, Andrew David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777601/ http://dx.doi.org/10.1093/ofid/ofaa439.1375 |
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