1642. A Novel β-lactamase Inhibitor (Durlobactam, DUR) and β-Lactams Enhance Susceptibility Against Multidrug-Resistant (MDR) Mycobacterium abscessus (Mab)

BACKGROUND: Mab is a MDR nontuberculous mycobacterium that causes lung infections in patients with structural lung disease. Mab harbors a chromosomally encoded class A β-lactamase, Bla(Mab), able to hydrolyze penicillins, cephalosporins and carbapenems. L,D- and D,D-transpeptidases (L,D TP and D,D T...

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Detalles Bibliográficos
Autores principales: Dousa, Khalid M, Kurz, Sebastian G, Bethel, Christopher, Miller, Alita, Bonomo, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777676/
http://dx.doi.org/10.1093/ofid/ofaa439.1822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777676/
http://dx.doi.org/10.1093/ofid/ofaa439.1822

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