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1614. Gwt1 Inhibitor, APX2104, Protects Against Invasive Aspergillosis in Neutropenic Mouse Model

BACKGROUND: Aspergillus fumigatus is the leading cause of invasive aspergillosis (IA), a lethal infection among immunocompromised patients. Guideline-recommended antifungal therapy against IA is a triazole antifungal, with other secondary options including an echinocandin and amphotericin B. Concern...

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Detalles Bibliográficos
Autores principales: Shaheen, Shareef, Allen, John, Cole, D Chris, Asfaw, Yohannes, Juvvadi, Praveen, Shwab, E Keats, Kapoor, Mili, Shaw, Karen, Steinbach, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777865/
http://dx.doi.org/10.1093/ofid/ofaa439.1794