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1614. Gwt1 Inhibitor, APX2104, Protects Against Invasive Aspergillosis in Neutropenic Mouse Model
BACKGROUND: Aspergillus fumigatus is the leading cause of invasive aspergillosis (IA), a lethal infection among immunocompromised patients. Guideline-recommended antifungal therapy against IA is a triazole antifungal, with other secondary options including an echinocandin and amphotericin B. Concern...
Autores principales: | Shaheen, Shareef, Allen, John, Cole, D Chris, Asfaw, Yohannes, Juvvadi, Praveen, Shwab, E Keats, Kapoor, Mili, Shaw, Karen, Steinbach, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777865/ http://dx.doi.org/10.1093/ofid/ofaa439.1794 |
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