255. Ticagrelor Aids Platelet-Mediated Clearance in a Refractory Staphylococcus aureus Endovascular Infection with Septic Emboli

BACKGROUND: The pore-forming alpha-toxin produced by Staphylococcus aureus (SA) decreases the viability and increases the clearance of platelets, a critical element of innate immune defense in endovascular infection. Our group recently identified that ticagrelor (TICA) blocks alpha-toxin-induced pla...

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Detalles Bibliográficos
Autores principales: Ulloa, Erlinda, Uchiyama, Satoshi, Nizet, Victor, Sakoulas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778142/
http://dx.doi.org/10.1093/ofid/ofaa439.299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778142/
http://dx.doi.org/10.1093/ofid/ofaa439.299

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