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Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression
The establishment and maintenance of chromatin domains shape the epigenetic memory of a cell, with the methylation of histone H3 lysine 9 (H3K9me) defining transcriptionally silent heterochromatin. We show here that the C. elegans SET-25 (SUV39/G9a) histone methyltransferase (HMT), which catalyzes H...
Autores principales: | Padeken, Jan, Methot, Stephen, Zeller, Peter, Delaney, Colin E., Kalck, Veronique, Gasser, Susan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778263/ https://www.ncbi.nlm.nih.gov/pubmed/33303642 http://dx.doi.org/10.1101/gad.344234.120 |
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