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Conserved Gsx2/Ind homeodomain monomer versus homodimer DNA binding defines regulatory outcomes in flies and mice

How homeodomain proteins gain sufficient specificity to control different cell fates has been a long-standing problem in developmental biology. The conserved Gsx homeodomain proteins regulate specific aspects of neural development in animals from flies to mammals, and yet they belong to a large tran...

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Detalles Bibliográficos
Autores principales: Salomone, Joseph, Qin, Shenyue, Fufa, Temesgen D., Cain, Brittany, Farrow, Edward, Guan, Bin, Hufnagel, Robert B., Nakafuku, Masato, Lim, Hee-Woong, Campbell, Kenneth, Gebelein, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778271/
https://www.ncbi.nlm.nih.gov/pubmed/33334823
http://dx.doi.org/10.1101/gad.343053.120