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507. Activation of Macrophages Enhances Susceptibility to SARS-CoV-2 Antibody-Dependent Enhancement and Promotes Damage to Downstream Epithelial Cells

BACKGROUND: The distinct shift in peripheral monocyte activation and infiltration of these cells into the respiratory tract observed in severe cases of COVID-19 suggests that like SARS-CoV-1, the acute respiratory distress syndrome (ARDs) observed in SARS-CoV-2 infections may result from damage to t...

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Detalles Bibliográficos
Autores principales: DeMarco, Jennifer K, Severson, William E, DeMarco, Daniel R, Gabbard, Jon, Palmer, Kenneth E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778276/
http://dx.doi.org/10.1093/ofid/ofaa439.701