Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance

Aims: Ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-AKI) is characterized by elevated levels of reactive oxygen species (ROS), mitochondrial dysfunction, and inflammation, but the potential link among these features remains unclear. In this study, we aimed to investigate the spe...

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Detalles Bibliográficos
Autores principales: Zhao, Meng, Wang, Yizhuo, Li, Ling, Liu, Shuyun, Wang, Chengshi, Yuan, Yujia, Yang, Guang, Chen, Younan, Cheng, Jingqiu, Lu, Yanrong, Liu, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778599/
https://www.ncbi.nlm.nih.gov/pubmed/33408785
http://dx.doi.org/10.7150/thno.50905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778599/
https://www.ncbi.nlm.nih.gov/pubmed/33408785
http://dx.doi.org/10.7150/thno.50905

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