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Immunomodulation by systemic administration of human-induced pluripotent stem cell-derived mesenchymal stromal cells to enhance the therapeutic efficacy of cell-based therapy for treatment of myocardial infarction

Rationale: Poor survival and engraftment are major hurdles of stem cell therapy in the treatment of myocardial infarction (MI). We sought to determine whether pre-transplantation systemic intravenous administration of human induced pluripotent stem cell (hiPSC)-derived mesenchymal stromal cells (hiP...

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Detalles Bibliográficos
Autores principales: Sun, Si-Jia, Lai, Wing-Hon, Jiang, Yu, Zhen, Zhe, Wei, Rui, Lian, Qizhou, Liao, Song-Yan, Tse, Hung-Fat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778603/
https://www.ncbi.nlm.nih.gov/pubmed/33408772
http://dx.doi.org/10.7150/thno.46119