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The β-Cell Genomic Landscape in T1D: Implications for Disease Pathogenesis
PURPOSE OF REVIEW: Type 1 diabetes (T1D) develops as a consequence of a combination of genetic predisposition and environmental factors. Combined, these events trigger an autoimmune disease that results in progressive loss of pancreatic β cells, leading to insulin deficiency. This article reviews th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778620/ https://www.ncbi.nlm.nih.gov/pubmed/33387073 http://dx.doi.org/10.1007/s11892-020-01370-4 |