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crisprSQL: a novel database platform for CRISPR/Cas off-target cleavage assays

With ongoing development of the CRISPR/Cas programmable nuclease system, applications in the area of in vivo therapeutic gene editing are increasingly within reach. However, non-negligible off-target effects remain a major concern for clinical applications. Even though a multitude of off-target clea...

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Detalles Bibliográficos
Autores principales: Störtz, Florian, Minary, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778913/
https://www.ncbi.nlm.nih.gov/pubmed/33084893
http://dx.doi.org/10.1093/nar/gkaa885