Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets

CRISPR genetic screens in cancer cell models are a powerful tool to elucidate oncogenic mechanisms and to identify promising therapeutic targets. The Project Score database (https://score.depmap.sanger.ac.uk/) uses genome-wide CRISPR–Cas9 dropout screening data in hundreds of highly annotated cancer...

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Detalles Bibliográficos
Autores principales: Dwane, Lisa, Behan, Fiona M, Gonçalves, Emanuel, Lightfoot, Howard, Yang, Wanjuan, van der Meer, Dieudonne, Shepherd, Rebecca, Pignatelli, Miguel, Iorio, Francesco, Garnett, Mathew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778984/
https://www.ncbi.nlm.nih.gov/pubmed/33068406
http://dx.doi.org/10.1093/nar/gkaa882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778984/
https://www.ncbi.nlm.nih.gov/pubmed/33068406
http://dx.doi.org/10.1093/nar/gkaa882

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