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The Nucleome Data Bank: web-based resources to simulate and analyze the three-dimensional genome

We introduce the Nucleome Data Bank (NDB), a web-based platform to simulate and analyze the three-dimensional (3D) organization of genomes. The NDB enables physics-based simulation of chromosomal structural dynamics through the MEGABASE + MiChroM computational pipeline. The input of the pipeline con...

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Detalles Bibliográficos
Autores principales: Contessoto, Vinícius G, Cheng, Ryan R, Hajitaheri, Arya, Dodero-Rojas, Esteban, Mello, Matheus F, Lieberman-Aiden, Erez, Wolynes, Peter G, Di Pierro, Michele, Onuchic, José N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778995/
https://www.ncbi.nlm.nih.gov/pubmed/33021634
http://dx.doi.org/10.1093/nar/gkaa818