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Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation

Despite the substantial advances in the management of metastatic melanoma with the introduction of immune checkpoint inhibitors (ICI), many patients develop disease progression during treatment with immunotherapy. This has been suggested to be mediated by several mechanisms that contribute to acquir...

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Detalles Bibliográficos
Autores principales: Khaddour, Karam, Dowling, Joshua, Huang, Jiayi, Council, Martha, Chen, David, Cornelius, Lynn, Johanns, Tanner, Dahiya, Sonika, Ansstas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779252/
https://www.ncbi.nlm.nih.gov/pubmed/33447351
http://dx.doi.org/10.18632/oncotarget.27848