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Backbone chemical shift assignments for the SARS-CoV-2 non-structural protein Nsp9: intermediate (ms – μs) dynamics in the C-terminal helix at the dimer interface

The Betacoronavirus SARS-CoV-2 non-structural protein Nsp9 is a 113-residue protein that is essential for viral replication, and consequently, a potential target for the development of therapeutics against COVID19 infections. To capture insights into the dynamics of the protein’s backbone in solutio...

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Detalles Bibliográficos
Autores principales: Buchko, Garry W., Zhou, Mowei, Craig, Justin K., Van Voorhis, Wesley C., Myler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779335/
https://www.ncbi.nlm.nih.gov/pubmed/33392924
http://dx.doi.org/10.1007/s12104-020-09992-1