Bidirectional Action of Cenicriviroc, a CCR2/CCR5 Antagonist, Results in Alleviation of Pain-Related Behaviors and Potentiation of Opioid Analgesia in Rats With Peripheral Neuropathy

Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the effects of available analgesics, including opioids. Converging evidence indicates the functional interactions between chemokine and opioid receptors and their influence on nociceptive processes. Recent stu...

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Detalles Bibliográficos
Autores principales: Kwiatkowski, Klaudia, Pawlik, Katarzyna, Ciapała, Katarzyna, Piotrowska, Anna, Makuch, Wioletta, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779470/
https://www.ncbi.nlm.nih.gov/pubmed/33408720
http://dx.doi.org/10.3389/fimmu.2020.615327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779470/
https://www.ncbi.nlm.nih.gov/pubmed/33408720
http://dx.doi.org/10.3389/fimmu.2020.615327

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