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Yeast microcapsule-mediated oral delivery of IL-1β shRNA for post-traumatic osteoarthritis therapy

Post-traumatic osteoarthritis is a prevalent debilitating joint disease. However, there is no FDA-approved disease-modifying osteoarthritis drug currently. Gene therapy can improve disease progression but lacks an effective delivery system. Here, we constructed an oral drug delivery system by non-vi...

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Detalles Bibliográficos
Autores principales: Zhang, Long, Peng, Hang, Feng, Meng, Zhang, Wan, Li, Yankun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779538/
https://www.ncbi.nlm.nih.gov/pubmed/33425491
http://dx.doi.org/10.1016/j.omtn.2020.11.006