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A computational framework for identifying the transcription factors involved in enhancer-promoter loop formation

The pairwise interaction between transcription factors (TFs) plays an important role in enhancer-promoter loop formation. Although thousands of TFs in the human genome have been found, only a few TF pairs have been demonstrated to be related to loop formation. It is still a challenge to determine wh...

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Detalles Bibliográficos
Autores principales: Liu, Li, Zhang, Li-Rong, Dao, Fu-Ying, Yang, Yan-Chao, Lin, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779541/
https://www.ncbi.nlm.nih.gov/pubmed/33425492
http://dx.doi.org/10.1016/j.omtn.2020.11.011