PSTi8 with metformin ameliorates perimenopause induced steatohepatitis associated ER stress by regulating SIRT-1/SREBP-1c axis

AIMS: Hepatic steatosis in women confronting menopause is the manifestation of substantial fructose consumption and forms a positive feedback loop to develop endoplasmic reticulum (ER) stress. Previously pancreastatin inhibitor peptide-8 (PSTi8) and Metformin (Met) combination effectively ameliorate...

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Detalles Bibliográficos
Autores principales: Singh, Pragati, Reza, Mohammad Irshad, Syed, Anees A., Garg, Richa, Husain, Athar, Katekar, Roshan, Goand, Umesh K., Riyazuddin, Mohammed, Gupta, Anand P., Gayen, Jiaur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779780/
https://www.ncbi.nlm.nih.gov/pubmed/33426334
http://dx.doi.org/10.1016/j.heliyon.2020.e05826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779780/
https://www.ncbi.nlm.nih.gov/pubmed/33426334
http://dx.doi.org/10.1016/j.heliyon.2020.e05826

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