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Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion

BACKGROUND & AIMS: Macrophages are key regulators of inflammation and cancer promotion in the liver, and their recruitment and activation is linked to chemokine receptor signaling. However, the exact roles of the chemokine receptors CCR2 and CCR5 for macrophage functions in the liver is obscure....

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Detalles Bibliográficos
Autores principales: Bartneck, Matthias, Koppe, Christiane, Fech, Viktor, Warzecha, Klaudia T., Kohlhepp, Marlene, Huss, Sebastian, Weiskirchen, Ralf, Trautwein, Christian, Luedde, Tom, Tacke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779787/
https://www.ncbi.nlm.nih.gov/pubmed/32896623
http://dx.doi.org/10.1016/j.jcmgh.2020.08.012