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Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion
BACKGROUND & AIMS: Macrophages are key regulators of inflammation and cancer promotion in the liver, and their recruitment and activation is linked to chemokine receptor signaling. However, the exact roles of the chemokine receptors CCR2 and CCR5 for macrophage functions in the liver is obscure....
Autores principales: | Bartneck, Matthias, Koppe, Christiane, Fech, Viktor, Warzecha, Klaudia T., Kohlhepp, Marlene, Huss, Sebastian, Weiskirchen, Ralf, Trautwein, Christian, Luedde, Tom, Tacke, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779787/ https://www.ncbi.nlm.nih.gov/pubmed/32896623 http://dx.doi.org/10.1016/j.jcmgh.2020.08.012 |
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