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Alpha Thalassemia/Intellectual Disability X-Linked Deficiency Sensitizes Non-Small Cell Lung Cancer to Immune Checkpoint Inhibitors

BACKGROUND: The immune checkpoint inhibitors (ICIs) have achieved great success in the treatment of non-small cell lung cancer (NSCLC) patients. However, the response rate is low. The molecular mechanism involved in the effectiveness of ICIs remains to be elucidated. METHODS: ATRX mutation incidence...

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Detalles Bibliográficos
Autores principales: Hou, Tao, Jiang, Shun, Wang, Yapeng, Xie, Yangchun, Zhang, Haixia, Feng, Yeqian, Ma, Fang, Ma, Jin’an, Liu, Xianling, Hu, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779797/
https://www.ncbi.nlm.nih.gov/pubmed/33409155
http://dx.doi.org/10.3389/fonc.2020.608300