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The Development of Integrin Alpha-8 Deficient Lungs Shows Reduced and Altered Branching and a Correction of the Phenotype During Alveolarization

Lung development involves epithelial–mesenchymal interactions and integrins represent one of the key elements. These extracellular matrix receptors form hetero-dimers of alpha and beta subunits. The integrin α8β1 is highly expressed in mouse tissues, including lung. It forms a cellular receptor for...

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Detalles Bibliográficos
Autores principales: Cremona, Tiziana P., Hartner, Andrea, Schittny, Johannes C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779808/
https://www.ncbi.nlm.nih.gov/pubmed/33408636
http://dx.doi.org/10.3389/fphys.2020.530635