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HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress
The advent of combined antiretroviral treatment (cART) as a treatment for HIV-1 infection has not only resulted in a dramatic decrease in the peripheral viral load but has also led to increased life expectancy of the infected individuals. Paradoxically, increased lifespan is accompanied with higher...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779826/ https://www.ncbi.nlm.nih.gov/pubmed/33385630 http://dx.doi.org/10.1016/j.redox.2020.101843 |