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HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress

The advent of combined antiretroviral treatment (cART) as a treatment for HIV-1 infection has not only resulted in a dramatic decrease in the peripheral viral load but has also led to increased life expectancy of the infected individuals. Paradoxically, increased lifespan is accompanied with higher...

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Detalles Bibliográficos
Autores principales: Thangaraj, Annadurai, Chivero, Ernest T., Tripathi, Ashutosh, Singh, Seema, Niu, Fang, Guo, Ming-Lei, Pillai, Prakash, Periyasamy, Palsamy, Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779826/
https://www.ncbi.nlm.nih.gov/pubmed/33385630
http://dx.doi.org/10.1016/j.redox.2020.101843