Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping

With the recent approval of 3 new antibody drug conjugates (ADCs) for solid tumors, this class of drugs is gaining momentum for the targeted treatment of cancer. Despite significant investment, there are still fundamental issues that are incompletely understood. Three of the recently approved ADCs c...

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Detalles Bibliográficos
Autores principales: Khera, Eshita, Cilliers, Cornelius, Smith, Michael D., Ganno, Michelle L., Lai, Katharine C., Keating, Thomas A., Kopp, Anna, Nessler, Ian, Abu-Yousif, Adnan O., Thurber, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779838/
https://www.ncbi.nlm.nih.gov/pubmed/33385970
http://dx.doi.org/10.1016/j.neo.2020.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779838/
https://www.ncbi.nlm.nih.gov/pubmed/33385970
http://dx.doi.org/10.1016/j.neo.2020.12.001

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