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Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping
With the recent approval of 3 new antibody drug conjugates (ADCs) for solid tumors, this class of drugs is gaining momentum for the targeted treatment of cancer. Despite significant investment, there are still fundamental issues that are incompletely understood. Three of the recently approved ADCs c...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779838/ https://www.ncbi.nlm.nih.gov/pubmed/33385970 http://dx.doi.org/10.1016/j.neo.2020.12.001 |