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Encapsulation of Low Metronidazole Dose in Poly (D,L-lactide-co-glycolide) (PLGA) Nanoparticles Improves Giardia intestinalis Treatment

BACKGROUND: The present study was designed to investigate the antigiardial efficacy of low metronidazole dose loaded-D.L-lactide-co-glycolide (LMD-PLGA) nanoparticles (NPs) and to compare it with the standard high dose of metronidazole either free (HMD) or loaded on PLGA (HMD-PLGA). MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales: Madbouly, Neveen Adel, Nashee, Hayam, Elgendy, Ashraf Ahmed, Rabee, Ibraheem, El Amir, Azza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases; Korean Society for Antimicrobial Therapy; The Korean Society for AIDS 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779986/
https://www.ncbi.nlm.nih.gov/pubmed/33377322
http://dx.doi.org/10.3947/ic.2020.52.4.550