Cargando…

Prolonged unfolded protein reaction is involved in the induction of chronic myeloid leukemia cell death upon oprozomib treatment

To select the most efficient chemical to induce apoptosis in leukemia cells, a multidrug screen was applied on bone marrow mononuclear cells from chronic myeloid leukemia (CML) patients. Oprozomib (Cpd 21) was chosen for the subsequent experiments. The isobaric tags for relative and absolute quantit...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Fang, Wang, Xin, Li, Na, Liu, Juan, Zhang, Lin, Hui, Lingyun, Feng, Ai, Wang, Zhonglin, Wang, Yawen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780017/
https://www.ncbi.nlm.nih.gov/pubmed/33067904
http://dx.doi.org/10.1111/cas.14696