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Bizarre giant cells in human angiosarcoma exhibit chemoresistance and contribute to poor survival outcomes

Giant cells (GC) are a poorly understood subset of tumor cells that have been increasingly recognized as a potential contributor to tumor heterogeneity and treatment resistance. We aimed to characterize the biological and clinical significance of GC in angiosarcoma, an aggressive rare cancer of endo...

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Detalles Bibliográficos
Autores principales: Tan, Grace Fangmin, Goh, Shane, Lim, Abner Herbert, Liu, Wei, Lee, Jing Yi, Rajasegaran, Vikneswari, Sam, Xin Xiu, Tay, Timothy Kwang Yong, Selvarajan, Sathiyamoorthy, Ng, Cedric Chuan‐Young, Teh, Bin Tean, Chan, Jason Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780052/
https://www.ncbi.nlm.nih.gov/pubmed/33164299
http://dx.doi.org/10.1111/cas.14726