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Hemagglutinating virus of Japan‐envelope containing programmed cell death‐ligand 1 siRNA inhibits immunosuppressive activities and elicits antitumor immune responses in glioma

The programmed cell death‐1/programmed cell death‐ligand 1 (PD‐1/PD‐L1) pathway is involved in preventing immune system‐mediated destruction of malignant tumors including glioblastoma. However, the therapeutic influence of PD‐1/PD‐L1 inhibition alone in glioblastoma is limited. To develop effective...

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Detalles Bibliográficos
Autores principales: Sugii, Narushi, Matsuda, Masahide, Okumura, Genki, Shibuya, Akira, Ishikawa, Eiichi, Kaneda, Yasufumi, Matsumura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780057/
https://www.ncbi.nlm.nih.gov/pubmed/33155337
http://dx.doi.org/10.1111/cas.14721