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Asn‐linked N–acetylglucosamine of the amylin receptor 2 extracellular domain enhances peptide ligand affinity
The calcitonin receptor (CTR) has a large extracellular domain (ECD) with multiple N‐glycosylation sites. An asparagine (Asn)‐linked N‐acetylglucosamine (GlcNAc) of CTR ECD N130 was previously reported to enhance peptide hormone binding affinity for CTR ECD. CTR forms a complex with an accessory pro...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780097/ https://www.ncbi.nlm.nih.gov/pubmed/33227824 http://dx.doi.org/10.1002/2211-5463.13042 |