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The p75(NTR) and its carboxyl‐terminal fragment exert opposing effects on melanoma cell proliferation and apoptosis via modulation of the NF‐κB pathway

The p75 neurotrophin receptor (p75(NTR)), a member of the tumor necrosis factor superfamily of receptors, is sensitive to proteolysis and has been observed to be expressed in various cancers. However, the roles of p75(NTR) and its proteolytic fragments in tumorigenesis remain incompletely understood...

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Detalles Bibliográficos
Autores principales: Zhong, Maojiao, Wang, Yingying, Muhammad, Farrukh Nisar, Gao, Jing, Bian, Chunxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780107/
https://www.ncbi.nlm.nih.gov/pubmed/33247998
http://dx.doi.org/10.1002/2211-5463.13047