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PGC‐1α is downregulated in a mouse model of obstructive cholestasis but not in a model of liver fibrosis

Several studies have indicated that cholestatic liver damage involves mitochondria dysfunction. However, the precise mechanism by which hydrophobic bile salts cause mitochondrial dysfunction is not clear. In this study, we intended to determine the pathogenesis of cholestatic liver injury associated...

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Detalles Bibliográficos
Autores principales: Park, Jung Hyun, Kwak, Bong Jun, Choi, Ho Joong, Kim, Ok‐Hee, Hong, Ha‐Eun, Lee, Sang Chul, Kim, Kee‐Hwan, You, Young Kyoung, Lee, Tae Yun, Ahn, Joseph, Kim, Say‐June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780111/
https://www.ncbi.nlm.nih.gov/pubmed/32860664
http://dx.doi.org/10.1002/2211-5463.12961