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PGC‐1α is downregulated in a mouse model of obstructive cholestasis but not in a model of liver fibrosis
Several studies have indicated that cholestatic liver damage involves mitochondria dysfunction. However, the precise mechanism by which hydrophobic bile salts cause mitochondrial dysfunction is not clear. In this study, we intended to determine the pathogenesis of cholestatic liver injury associated...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780111/ https://www.ncbi.nlm.nih.gov/pubmed/32860664 http://dx.doi.org/10.1002/2211-5463.12961 |