The CAG promoter maintains high‐level transgene expression in HEK293 cells

The vast majority of therapeutic recombinant proteins are produced in mammalian cell lines. However, proteins generated in nonhuman cell lines, such as Chinese hamster ovary (CHO) cells, are decorated with human‐like glycan structures that differ from those of human cells, and these may induce immun...

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Detalles Bibliográficos
Autores principales: Dou, Yuanyuan, Lin, Yan, Wang, Tian‐yun, Wang, Xiao‐Yin, Jia, Yan‐long, Zhao, Chun‐peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780116/
https://www.ncbi.nlm.nih.gov/pubmed/33155423
http://dx.doi.org/10.1002/2211-5463.13029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780116/
https://www.ncbi.nlm.nih.gov/pubmed/33155423
http://dx.doi.org/10.1002/2211-5463.13029

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