Modulators of histone demethylase JMJD1C selectively target leukemic stem cells

Leukemic stem cells (LSCs) comprise a very rare cell population that results in the development of acute myeloid leukemia. The selective targeting of drivers in LSCs with small molecule inhibitors holds promise for treatment of acute myeloid leukemia. Recently, we reported the identification of inhi...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Zhang, Xinjing, Zhang, Xiaoyan, Wang, Yishu, Wang, Xintong, Hu, Linda, Zhao, Yao, Wang, Haihua, Wang, Zhanju, Wang, Haiying, Wang, Lin, Dirks, Wilhelm G., Drexler, Hans G., Xu, Xin, Hu, Zhenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780120/
https://www.ncbi.nlm.nih.gov/pubmed/33289299
http://dx.doi.org/10.1002/2211-5463.13054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780120/
https://www.ncbi.nlm.nih.gov/pubmed/33289299
http://dx.doi.org/10.1002/2211-5463.13054

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