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Biomechanical Forces Regulate Gene Transcription During Stretch-Mediated Growth of Mammalian Neurons

At birth, there are 100 billion neurons in the human brain, with functional neural circuits extending through the spine to the epidermis of the feet and toes. Following birth, limbs and vertebrae continue to grow by several orders of magnitude, forcing established axons to grow by up to 200 cm in le...

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Detalles Bibliográficos
Autores principales: Loverde, Joseph R., Tolentino, Rosa E., Soteropoulos, Patricia, Pfister, Bryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780124/
https://www.ncbi.nlm.nih.gov/pubmed/33408609
http://dx.doi.org/10.3389/fnins.2020.600136