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Clustering and reverse transcription of HIV‐1 genomes in nuclear niches of macrophages

In order to replicate, human immunodeficiency virus (HIV‐1) reverse‐transcribes its RNA genome into DNA, which subsequently integrates into host cell chromosomes. These two key events of the viral life cycle are commonly viewed as separate not only in time, but also in cellular space, since reverse...

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Detalles Bibliográficos
Autores principales: Rensen, Elena, Mueller, Florian, Scoca, Viviana, Parmar, Jyotsana J, Souque, Philippe, Zimmer, Christophe, Di Nunzio, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780146/
https://www.ncbi.nlm.nih.gov/pubmed/33270250
http://dx.doi.org/10.15252/embj.2020105247