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NF-κB signalling as a pharmacological target in COVID-19: potential roles for IKKβ inhibitors
Coronavirus disease 2019 (COVID-19) has been characterized by lymphopenia as well as a proinflammatory cytokine storm, which are responsible for the poor prognosis and multiorgan defects. The transcription factor nuclear factor-κB (NF-κB) modulates the functions of the immune cells and alters the ge...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780215/ https://www.ncbi.nlm.nih.gov/pubmed/33394134 http://dx.doi.org/10.1007/s00210-020-02035-5 |