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NF-κB signalling as a pharmacological target in COVID-19: potential roles for IKKβ inhibitors

Coronavirus disease 2019 (COVID-19) has been characterized by lymphopenia as well as a proinflammatory cytokine storm, which are responsible for the poor prognosis and multiorgan defects. The transcription factor nuclear factor-κB (NF-κB) modulates the functions of the immune cells and alters the ge...

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Detalles Bibliográficos
Autor principal: Kandasamy, Mahesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780215/
https://www.ncbi.nlm.nih.gov/pubmed/33394134
http://dx.doi.org/10.1007/s00210-020-02035-5