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Computational screening for potential drug candidates against the SARS-CoV-2 main protease

Background: SARS-CoV-2 is the causal agent of the current coronavirus disease 2019 (COVID-19) pandemic. They are enveloped, positive-sense, single-stranded RNA viruses of the Coronaviridae family. Proteases of SARS-CoV-2 are necessary for viral replication, structural assembly, and pathogenicity. Th...

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Detalles Bibliográficos
Autores principales: Silva Andrade, Bruno, Ghosh, Preetam, Barh, Debmalya, Tiwari, Sandeep, José Santana Silva, Raner, Rodrigues de Assis Soares, Wagner, Silva Melo, Tarcisio, Santos Freitas, Andria, González-Grande, Patrícia, Sousa Palmeira, Lucas, Carlos Junior Alcantara, Luiz, Giovanetti, Marta, Góes-Neto, Aristóteles, Ariston de Carvalho Azevedo, Vasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780344/
https://www.ncbi.nlm.nih.gov/pubmed/33447372
http://dx.doi.org/10.12688/f1000research.23829.2