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Computational screening for potential drug candidates against the SARS-CoV-2 main protease
Background: SARS-CoV-2 is the causal agent of the current coronavirus disease 2019 (COVID-19) pandemic. They are enveloped, positive-sense, single-stranded RNA viruses of the Coronaviridae family. Proteases of SARS-CoV-2 are necessary for viral replication, structural assembly, and pathogenicity. Th...
Autores principales: | Silva Andrade, Bruno, Ghosh, Preetam, Barh, Debmalya, Tiwari, Sandeep, José Santana Silva, Raner, Rodrigues de Assis Soares, Wagner, Silva Melo, Tarcisio, Santos Freitas, Andria, González-Grande, Patrícia, Sousa Palmeira, Lucas, Carlos Junior Alcantara, Luiz, Giovanetti, Marta, Góes-Neto, Aristóteles, Ariston de Carvalho Azevedo, Vasco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780344/ https://www.ncbi.nlm.nih.gov/pubmed/33447372 http://dx.doi.org/10.12688/f1000research.23829.2 |
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