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Silencing Nrf2 attenuates chronic suppurative otitis media by inhibiting pro-inflammatory cytokine secretion through up-regulating TLR4

Compromised TLR-mediated chronic inflammation contributes to bacterial infection-caused chronic suppurative otitis media, but the mechanisms are unclear. The present study examined the expression status of nuclear erythroid 2-related factor 2 (Nrf2) and TLRs in human middle-ear mucosae tissues colle...

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Detalles Bibliográficos
Autores principales: Tuoheti, Abulajiang, Gu, Xingzhi, Cheng, Xiuqin, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780353/
https://www.ncbi.nlm.nih.gov/pubmed/32579053
http://dx.doi.org/10.1177/1753425920933661