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Silencing Nrf2 attenuates chronic suppurative otitis media by inhibiting pro-inflammatory cytokine secretion through up-regulating TLR4
Compromised TLR-mediated chronic inflammation contributes to bacterial infection-caused chronic suppurative otitis media, but the mechanisms are unclear. The present study examined the expression status of nuclear erythroid 2-related factor 2 (Nrf2) and TLRs in human middle-ear mucosae tissues colle...
Autores principales: | Tuoheti, Abulajiang, Gu, Xingzhi, Cheng, Xiuqin, Zhang, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780353/ https://www.ncbi.nlm.nih.gov/pubmed/32579053 http://dx.doi.org/10.1177/1753425920933661 |
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