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ASC-J9® suppresses prostate cancer cell proliferation and invasion via altering the ATF3-PTK2 signaling

BACKGROUND: Early studies indicated that ASC-J9®, an androgen receptor (AR) degradation enhancer, could suppress the prostate cancer (PCa) progression. Here we found ASC-J9® could also suppress the PCa progression via an AR-independent mechanism, which might involve modulating the tumor suppressor A...

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Detalles Bibliográficos
Autores principales: Tian, Hao, Chou, Fu-ju, Tian, Jing, Zhang, Yong, You, Bosen, Huang, Chi-Ping, Yeh, Shuyuan, Niu, Yuanjie, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780640/
https://www.ncbi.nlm.nih.gov/pubmed/33390173
http://dx.doi.org/10.1186/s13046-020-01760-2