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Four subgroups based on tau levels in Alzheimer’s disease observed in two independent cohorts

BACKGROUND: As Alzheimer’s disease (AD) pathology presents decades before dementia manifests, unbiased biomarker cut-points may more closely reflect presence of pathology than clinically defined cut-points. Currently, unbiased cerebrospinal fluid (CSF) tau cut-points are lacking. METHODS: We investi...

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Detalles Bibliográficos
Autores principales: Duits, Flora H., Wesenhagen, Kirsten E. J., Ekblad, Laura, Wolters, Emma, Willemse, Eline A. J., Scheltens, Philip, van der Flier, Wiesje M., Teunissen, Charlotte E., Visser, Pieter Jelle, Tijms, Betty M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780683/
https://www.ncbi.nlm.nih.gov/pubmed/33397464
http://dx.doi.org/10.1186/s13195-020-00713-3