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LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM

De novo and acquired resistance, which are mainly mediated by genetic alterations, are barriers to effective routine chemotherapy. However, the mechanisms underlying gastric cancer (GC) resistance to chemotherapy are still unclear. We showed that the long noncoding RNA CRNDE was related to the chemo...

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Detalles Bibliográficos
Autores principales: Zhang, Feifei, Wang, Hui, Yu, Jiang, Yao, Xueqing, Yang, Shibin, Li, Weidong, Xu, Lijun, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780690/
https://www.ncbi.nlm.nih.gov/pubmed/33397371
http://dx.doi.org/10.1186/s12943-020-01299-y